| Player | Total | PL | ECL | FA Cup | League Cup | Other |
| Wayne Rooney | 22 | 17 | 3 | 2 | 0 | 0 |
| Dimitar Berbatov | 9 | 7 | 1 | 0 | 1 | 0 |
| Daniel Welbeck | 9 | 6 | 2 | 1 | 0 | 0 |
| Luis Nani | 8 | 6 | 0 | 0 | 0 | 2 |
| Javier Hernandez | 8 | 8 | 0 | 0 | 0 | 0 |
| Antonio Valencia | 4 | 2 | 1 | 0 | 1 | 0 |
| Ashley Young | 3 | 2 | 1 | 0 | 0 | 0 |
| Ji-Sung Park | 3 | 2 | 0 | 1 | 0 | 0 |
| Ryan Giggs | 3 | 1 | 1 | 0 | 1 | 0 |
| Michael Owen | 3 | 0 | 0 | 0 | 3 | 0 |
| Chris Smalling | 2 | 1 | 0 | 0 | 0 | 1 |
| Phil Jones | 2 | 1 | 1 | 0 | 0 | 0 |
| Own Goal | 2 | 2 | 0 | 0 | 0 | 0 |
| Michael Carrick | 2 | 2 | 0 | 0 | 0 | 0 |
| Oliveira Anderson | 2 | 2 | 0 | 0 | 0 | 0 |
| Darren Fletcher | 2 | 1 | 1 | 0 | 0 | 0 |
| Federico Macheda | 1 | 0 | 0 | 0 | 1 | 0 |
| Paul Scholes | 1 | 1 | 0 | 0 | 0 | 0 |
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